Biomembranes: Molecular Structure and Function by Robert B. Gennis

By Robert B. Gennis

New textbooks in any respect degrees of chemistry seem with nice regularity. a few fields like simple biochemistry, natural response mechanisms, and chemical thermody­ namics are good represented through many glorious texts, and new or revised variants are released sufficiently frequently to maintain with development in examine. even if, a few parts of chemistry, specifically a lot of these taught on the graduate point, be afflicted by a true loss of updated textbooks. the main critical wishes ensue in fields which are swiftly altering. Textbooks in those topics frequently need to be written through scientists truly desirous about the study that's advancing the sphere. it's not frequently effortless to cajole such participants to set time apart to assist unfold the information they've got accrued. Our objective, during this sequence, is to pinpoint parts of chemistry the place fresh development has outpaced what's lined in any to be had textbooks, after which hunt down and convince specialists in those fields to supply rather concise yet instructive introductions to their fields. those may still serve the desires of 1 semester or one sector graduate classes in chemistry and biochemistry. occasionally, the provision of texts in lively learn parts might actually help stimulate the production of recent courses.

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In some cases, it is difficult to distinguish proteins which should properly be considered as membrane components from cytoplasmic proteins which may bind adventitiously to the membrane surface during the isolation procedures. 51 Membrane Lipids The most striking feature of membrane lipids is their enormous diversity. 52). Certainly the major role of membrane lipids is to form the bilayer matrix with which the proteins interact. 8 and are briefly discussed below. Glycerophosphol ipids These are the most commonly found membrane lipids.

13). 14. Structures of three sterols found in the membranes of eukaryotic cells. ceramides are generally known as cere bros ides. Gangliosides are a class of anionic glycosphingolipids that contain one or more molecules of sialic acid (Nacetylneuraminic acid, NeuNAc) linked to the sugar residues of a ceramide oligosaccharide. Globosides refer to neutral glycosphingolipids which do not contain the negatively charged sialic acid residues. , epithelial plasma membrane (849)J. Monogalactosyl ceramide is the largest single component of myelin sheath of nerve.

They are a significant component of the mitochondrial inner membrane, chloroplast membrane, and some bacterial membranes, but are rare in other membranes. (d) P lasmalogens. 10). Ethanolamine plasmalogens are an important component of myelin and of the cardiac sarcoplasmic reticulum (554). 6 16: 15: 14: 'Data from ref. 1570. ER denotes endoplasmic reticulum. 6. , §i" ~. /O - y ? 11. (A) Some less common acyl- and ether-linked hydrocarbon chains in the membrane lipids of bacteria. , thermophiles, acidophiles, and halophiles (see 1262,307, 888 for reviews).

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