Cellular Biophysics, Vol. 2: Electrical Properties by Thomas Fischer Weiss

By Thomas Fischer Weiss

Cellular Biophysics is a quantitatively orientated uncomplicated body structure textual content for senior undergraduate and graduate scholars in bioengineering, biophysics, body structure, and neuroscience courses. it is going to additionally function an enormous reference paintings for biophysicists.Developed from the author's notes for a path that he has taught at MIT for a few years, those books supply a transparent and logical clarification of the rules of cellphone biophysics, educating delivery and houses of cells from a mixed organic, actual, and engineering viewpoint.Each quantity includes introductory chapters that encourage the fabric and current it in a large historic context. vital experimental effects and techniques are defined. Theories are derived in general from first rules in order that scholars improve an realizing of not just the predictions of the idea but in addition its obstacles. Theoretical effects are in comparison conscientiously with experimental findings and new effects look all through. there are numerous time-tested workouts and difficulties in addition to large lists of references.The quantity at the electric houses of cells covers either electrically inexcitable cells in addition to electrically excitable cells resembling neurons and muscle cells. integrated are chapters on lumped-parameter and distributed-parameter types of cells, linear electrical houses of cells, the Hodgkin-Huxley version of the large axon of the squid, saltatory conduction in myelinated nerve fibers, and voltage-gated ion channels.

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A. B. and Sato, M. (1953). ]. , 122:610-636. 44 Introduction to Electrical Properties of Cells Hodgkin, A. L. and Horowicz, P. (1959). ]. , 148:127-160. Hodgkin, A L. and Huxley, A F. (1939). Action potentials recorded from inside a nerve fibre. Nature, 144:710-711. , Huxley, A. , and Katz, B. (1952). Measurement of current-voltage relations in the membrane of the giant axon of Loligo. ]. , 116:424-448. Holton, T. and Weiss, T. F. (1983). Receptor potentials of lizard cochlear hair cells with free-standing stereocilia in response to tones.

8). \z rraz' where Pi is the resistivity of the inner conductor (cytoplasm). Thus, for the resistance per unit length we obtain the expression L\Ri Pi Yi=--=--. 11) where Yo is the resistance per unit length of the annular external conductor. 13) ;~- Io(Z, t) = Km(Z, t)- Ke(Z, t), + ~z. 14) . 18) z, , = Vi(Z, t)- V 0 (Z, t). 22) These equations constitute a distributed-parameter model of the relation of voltages and currents. However, these equations have quite different general validities. , V' · J = 0, without any further assumptions.

F. (1983). Receptor potentials of lizard cochlear hair cells with free-standing stereocilia in response to tones. ]. , 345:205-240. Hudspeth, A. J. P. (1977). Sensitivity, polarity, and conductance change in the response of vertebrate hair cells to controlled mechanical stimuli. Proc. Natl. Acad. Sd. , 74:2407-2411. Kiang, N. Y. S. (1975). Stimulus representation in the discharge patterns of auditory neurons. In Eagles, E. L. and Tower, D. , The Nervous System, vol. 3, Human Communication and Its Disorders, 81-96.

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