By Ad Rijnberk, Hans S. Kooistra
This hugely illustrated textbook is geared toward the veterinarian in perform or education drawn to all kinds of endocrine illnesses of canine and cats. The e-book is organised via physique approach and is case oriented.
Chapters take care of separate endocrine glands, starting with a quick assessment of the morphology and body structure of the gland, entire with drawings depicting the practical ideas. this can be by way of descriptions of the problems of the gland with updated info on prognosis and treatment.
Numerous medical circumstances illustrate the featuring indicators and the consequences following therapy. the ultimate chapters comprise diagnostic and healing protocols, in addition to algorithms for difficulties reminiscent of alopecia, polyuria, and weightloss.
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Additional info for Clinical Endocrinology of Dogs and Cats: An Illustrated Text, Second, Revised and Extended Edition
There is usually no remarkable delay in dentition. Unilateral or bilateral cryptorchidism is common in males and the females often have frequent anovulatory estrous cycles. Initially the dwarfed dogs are lively and alert – they can be amusing and even quite appealing – but eventually they become lethargic, lose appetite, and turn into thin, dull, almost hairless animals with a sad appearance. This stage usually appears by the age of two to three years and is commonly associated with severe secondary hypothyroidism and impaired renal function.
Modulation of the amount of mRNA, the efficiency of transcription and translation, the processing from preprohormone to hormone, and intracellular degradation of stored hormone determine, separately or jointly, the amount of hormone available for release. The hypophysiotropic hormones whose structures have been elucidated are, with one exception, peptides with sequence lengths ranging from 3–44 amino acids (fig. 8). Species variation in amino acid sequences can occur with increasing length. Whereas the structures of TRH, GnRH, and somatostatin (three, ten, and 14 amino acids, respectively) are identical in all mammals studied, the structure of GHRH varies.
9 The only nonpeptide hypophysiotropic hormone is dopamine. In addition to its major role as a neurotransmitter, it is the most important inhibitor of prolactin (PRL) secretion. The existence of a separate PRL-releasing hormone has long been a matter of debate. 7: Schematic illustration of the hypophysiotropic regulation of the secretion of hormones by the adenohypophysis. AVP = arginine-vasopressin; CRH = corticotropin-releasing hormone; GnRH = gonadotropin-releasing hormone; GHRH = growth hormone-releasing hormone; TRH = thyrotropin-releasing hormone; PrRP = prolactin-releasing peptide; PIF(DA) = prolactin-inhibiting factor (dopamine); ACTH = adrenocorticotropic hormone; LH = luteinizing hormone; FSH = follicle-stimulating hormone; GH = growth hormone; TSH = thyroid-stimulating hormone; PRL = prolactin; a-MSH = a-melanocyte-stimulating hormone; IGF-I = insulin-like growth factor-I.