By Felix Bronner and Arnost Kleinzeller (Eds.)
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Additional resources for Current Topics in Membranes and Transport, Vol. 1
Some confusion seems to exist in comparing the septate junction of vertebrates with the nexus or tight junction. Clearly, they are structurally distinct and any functional comparison is difficult at present. In any event, based on this fragmentary information, it appears that intermembrane bonding probably involves polar interactions between the outer lamellae of the adjacent membranes. That the lipid layers are relatively undisturbed by the fusion is indicated by the usual uniform appearance of the light region of both membranes.
M e d . 41, 439. Gras, W. , and Worthington, C. R. (1969). Proc. Nat. Acad. Sci. U . S. 63, 233. Gray, E. G. ( 1961). In “Electron Microscopy in Anatomy” (J. D. Boyd, F. R. Johnson, and J. D. ), pp. 54-73. Arnold, London. Green, D. , and Fleischer, S. ( 1964). In “Metabolism and Physiological Significance of Lipids” ( R . M. C. Dawson and D. N. ), pp. 581-617. Wiley, New York. Green, D. , and Goldberger, R. (1967). ” Academic Press, New York. Green, D. , and Pwdue, J. F. (1966). Proc. Nut. Acad.
4. GROUPTRANSLOCATION Another transport mechanism which is metabolically dependent is group translocation. In this process a covalent change is exerted upon the transported molecule such that the reaction itself results in the passage of the molecule through the diffusion barrier. Group translocation is not a classic active transport mechanism since the transported solute has been modified chemically. One such group translocation mechanism, which shall be called vectorial phosphorylation, leads to the translocation and H.