Endocrinology for the Small Animal Practitioner by David Panciera

By David Panciera

''A sensible consultant to the analysis, therapy and long-term care of canine and cats with endocrine disorder. contains actual exam laboratory checking out, diagnostic imaging, all authorized medications and administration of complications.''--Publisher's website.

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Atrial premature contractions and other supraventricular arrhythmias are more common than ventricular arrhythmias. Arterial Blood Pressure ✓ Should be measured in all cases. Very important if signs of hypertension are present (neurologic signs, retinal effusion, hemorrhage or detachment). Specific Tests for Diagnosis Primary Tests ♥ Hyperthyroidism is usually readily diagnosed by documenting elevated serum total T4 concentration. Cats with a normal serum T4 and clinical signs of hyperthyroidism may have mild hyperthyroidism, hyperthyroidism with a concurrent nonthyroidal illness, or a disease other than hyperthyroidism.

Serum Free Thyroxine (fT4) Concentration by Equilibrium Dialysis Overview ✓ Serum fT4 is a sensitive and relatively specific test for diagnosis of hypothyroidism when the assay is performed using the equilibrium dialysis technique. If the equilibrium dialysis technique is not used, measurement of fT4 is of no advantage over that of total T4. ✓ Free T4 less affected by nonthyroidal factors than serum total T4. Interpretation ♥ Serum fT4 has a similar sensitivity to total T4, being decreased in 90-98% of hypothyroid dogs.

Other methods for estimating free T4 do not offer an advantage over measurement of total T4. Interpretation ✓ Elevated free T4 in a cat without a concurrent nonthyroidal illness is diagnostic of hyperthyroidism. ♥ Free T4 may be invalid in cats with nonthyroidal illness, so fully evaluate the cat for other illnesses when using this test. Limitations ♥ Elevated in 6-12% of cats with nonthyroidal illness, including some cats with mild illness. A misdiagnosis can be made in this situation, so always combine free T4 measurement with a serum total T4.

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