Microarrays: Volume 1: Synthesis Methods by Hartmut Seliger (auth.), Jang B. Rampal (eds.)

By Hartmut Seliger (auth.), Jang B. Rampal (eds.)

Microarray expertise, Volumes 1 and a couple of, current info in designing and fabricating arrays and binding stories with organic analytes whereas supplying the reader with a vast description of microarray know-how instruments and their strength purposes. the 1st quantity offers with equipment and protocols for the coaching of microarrays. the second one quantity info functions and information research, that is very important in interpreting the big information popping out of microarray experiments.

Among the themes mentioned in quantity 1: Synthesis equipment, are matrices within the synthesis of microarrays, array optimization procedures, array-based comparative genomic hybridization, 60-mer oligonucleotide probes, bifunctional reagents NTMTA and NTPAC, and excessive density arrays utilizing electronic microarray synthesis systems. different subject matters contain multiplex ligation-dependent probe amplification (MLPA), hybridization stipulations in situ-synthesized oligo arrays, peptide arrays, excessive density replication instruments (HDRT), protocols for the quantification of oligo hybridization, glyco-bead arrays, and an research into the rising nano technology.

Microarray know-how, Volumes 1 and a pair of, offer abundant details to all degrees of scientists from beginner to these in detail accustomed to array technology.

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60, 6270–6276. 68. Beier, M. and Hoheisel, J. D. (1999) New developments in light-controlled synthesis of DNA-arrays. Nucleosides Nucleotides 18, 1301–1304. 69. , and Steiner, U. E. (2001) Photolabile protecting groups for nucleosides: mechanistic studies of the 2-(2-nitrophenyl)ethyl group. Helv. Chim. Acta 84, 1601–1611. 70. Beecher, J. , McGall, G. , and Goldberg, M. J. (1997) Chemically amplified photolithography for the fabrication of high density oligonucleotide arrays. Polymeric Mater. Sci.

17, 217–218. 12. Lockhart, D. J. and Winzeler, E. A. (2000) Genomics, gene expression and DNA arrays. Nature 405, 827–836. 13. Schena, M. ) (2002) Microarray Analysis. Wiley & Sons, New York. 14. Schena, M. and Davies, R. W. ), Oxford University Press, New York, pp. 1–16. 15. Lipshutz, R. , Fodor, S. P. , Gingeras, T. , and Lockhart, D. J. (1999) High density synthetic oligonucleotide arrays. Nat. Genet. Suppl. 21, 20–24. 16. McGall, G. H. and Christians, F. C. (2002) High-density genechip oligonucleotide probe arrays.

108. , et al. (2001) The use and evaluation of 2 + 2 photoaddition in immobilization of oligonucleotides on a three dimensional hydrogel matrix. Nucleosides Nucleotides Nucleic Acids 20, 1371–1375. 109. , Striebel, H. , and Stelzner, A. (2002) New ways to immobilize oligonucleotides on DNA-Chips. Collect. Czech. Chem. , Symp. Ser. 5, 299–303. 110. , Davis, R. , and Brown, P. O. (1995) Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science 270, 467–470. 111.

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