Molecular Biology of Cardiac Development and Growth by Paul J. R. Barton Ph.D., Kenneth R. Boheler Ph.D., Nigel J.

By Paul J. R. Barton Ph.D., Kenneth R. Boheler Ph.D., Nigel J. Brand Ph.D., Penny S. Thomas D.Phil. (auth.)

This ebook is worried with simple molecular biology and the way examine during this box pertains to our realizing of molecular and mobile elements of cardiac improvement and development. The authors indicate that molecular biology has supplied a wealth of latest methods for investigating mobile strategies on the molecular point and is now creating a major contribution to the knowledge of the molecular mechanisms underlying cardiac improvement and supplying perception into the molecular occasions underlying cardiac malformation and affliction. This quantity combines simple details on molecular biology with present pondering in cardiac improvement. it's the simply ebook to particularly do this.

Show description

Read Online or Download Molecular Biology of Cardiac Development and Growth PDF

Best biology books

Translation Initiation: Extract Systems and Molecular Genetics

For over fifty years the equipment in Enzymology sequence has been the significantly aclaimed laboratory common and the most revered courses within the box of biochemistry. The hugely appropriate fabric makes it a necessary ebook for researchers in all fields of existence and comparable sciences.

Evolutionary biology of ostracoda: its fundamentals and applications: Proceedings of the Ninth International Symposium on Ostracoda

There are lots of aggressive works out there bearing on evolutionary biology, yet this quantity is sort of targeted in its idiographic element concentrating on Ostracoda considered from a variety of disciplines, a while and environments. The booklet bargains with a variety of traces of idiographic biology and palaeontology of Ostracoda and nomothetic trials focusing strongly on evolutionary biology.

Liposomes: Methods and Protocols, Volume 2: Biological Membrane Models

With approximately 100 years of in depth learn, lipids have confirmed to be a necessary and ever-more-promising sector of mobilephone organic study. In Liposomes: tools and Protocols, major specialists within the comparable fields discover state of the art experimental tools concerning all elements of lipids as crucial parts of the phone membrane.

Fungi : biology and applications

Fungi: Biology and functions, moment Edition€provides a entire remedy of fungi, protecting biochemistry, genetics and the scientific and financial value of those organisms at introductory point. € without earlier wisdom of the topic assumed, the outlet chapters supply a extensive assessment of the fundamentals of fungal biology, specifically the body structure and genetics of fungi and in addition a brand new bankruptcy at the program of genomics to fungi.

Additional resources for Molecular Biology of Cardiac Development and Growth

Example text

Differentiation of HH stage 4 chick mesoderm explants under specific culture conditions into MHCpositive, beating cells does not occur in the presence of 40llM BrdU, but that of HH stage 6 explants does sometimes. 62 When cultured in the presence of dopamine, cell fate of chick HH stage 4 embryo aggregates can be almost exclusively cardiac myocytes. t Removal of the endoderm layer, leaving ectoderm overlying the HH stage 4+ to 5+ quail cardiac precursor region of mesoderm, almost completely inhibits development of the myocyte phenotype, possibly because the cells die, and often results in floating, vesicular structures.

A simple general description of development of a four-chambered heart, concentrating on morphological features, is followed by consideration of a number of morphological and functional events, and a discussion of the role of transcription factors in the onset of the cardiac phenotype and regionalization within the heart. AN OVERVIEW OF HEART DEVELOPMENT Terms such as 'atrial' or 'left ventricular' are used to describe regions of the developing heart prior to the presence of mature compartmental structure.

20. Zhu H, Nguyen VT, Brown AB et aI. A novel, tissue-restricted zinc finger protein (HF-lb) binds to the cardiac regulatory element (HF-1b/MEF2) in the rat myosin light-chain 2 gene. Mol Cell Bioi 1993; 13:4432-44. 21. Vallee BL, Coleman JE, Auld OS. Zinc fingers, zinc clusters and zinc twists in DNA-binding protein domains. Proc Nat! Acad Sci USA 1991; 88:999-1003. 22. Schwabe JWR, Rhodes D. Beyond zinc fingers: steroid hormone receptors have a novel structural motif for DNA recognition. Trends Biochem Sciences 1991; 16:291-6.

Download PDF sample

Rated 4.75 of 5 – based on 14 votes