Molecular Biology of the Cell by Bruce Alberts, Alexander Johnson, Julian Lewis, David

By Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

As the quantity of data in biology expands dramatically, it turns into more and more vital for textbooks to distill the gigantic quantity of clinical wisdom into concise rules and enduring concepts.As with past versions, Molecular Biology of the Cell, 6th variation accomplishes this objective with transparent writing and lovely illustrations. The 6th variation has been largely revised and up to date with the most recent learn within the box of phone biology, and it presents a good framework for educating and studying.

The complete representation software has been enormously enhanced.Protein buildings greater illustrate structure–function relationships, icons are less complicated and extra constant inside of and among chapters, and micrographs were refreshed and up to date with more recent, clearer, or larger photos. As a brand new characteristic, each one bankruptcy now includes exciting openended questions highlighting “What We Don’t Know,” introducing scholars to tough components of destiny examine. up to date end-of-chapter difficulties replicate new examine mentioned within the textual content, and those difficulties were improved to all chapters via including questions about developmental biology, tissues and stem cells, pathogens, and the immune system.

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In the living cell, however, DNA is not synthesized as a free strand in isolation, but on a template formed by a preexisting DNA strand. The bases protruding from the T C G A C C A Figure 1–2 DNA and its building blocks. (A) DNA is made from simple subunits, called nucleotides, each consisting of a sugar-phosphate molecule with a nitrogencontaining side group, or base, attached to it. The bases are of four types (adenine, guanine, cytosine, and thymine), corresponding to four distinct nucleotides, labeled A, G, C, and T.

9). ) The monomers of protein, the amino acids, are quite different from those of DNA and RNA, and there are 20 types instead of 4. Each amino acid is built around the same core structure through which it can be linked in a standard way to any other amino acid in the set; attached to this core is a side group that gives each amino acid a distinctive chemical character. Each of the protein molecules is a polypeptide, created by joining its amino acids in a particular sequence. Through billions of years of evolution, this sequence has been selected to give the protein a useful function.

Martin, Science 209:768–776, 1980. With permission from AAAS; D, courtesy of O. 5 billion years. It is scarcely to be expected that they would all store their information in the same form, or that the archives of one type of cell should be readable by the information-handling machinery of another. And yet it is so. All living cells on Earth store their hereditary information in the form of double-stranded molecules of DNA—long, unbranched, paired polymer chains, formed always of the same four types of monomers.

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